Armored RNA Quant® SARS-CoV-2
Asuragen has developed molecular diagnostic controls for multiple regions of the SARS-CoV-2 genome including mutations in the spike protein prevalent in the Alpha (B.1.1.7), Beta (B.1.351), Gamma (B.1.1.28), Delta (B.1.617.2), and Omicron (B.1.1.529) strains. Armored RNA Quant® controls allow for stable, reliable and safe ways to rapidly test for the presence of SARS-CoV-2 and its variants.
Each control encodes in vitro transcribed RNA encapsulated in a protective protein coat to create a virus-like particle resistant to nuclease degradation. This allows the product to be used as RNA extraction controls, process quality controls, or positive diagnostic reference controls. From feasibility to clinical use, these robust and versatile controls are beneficial across all sectors of the research and diagnostic spectrum.
Armored RNA Quant® SARS-CoV-2 Controls
- Concentration: 1 x 106 copies/mL and can be customized
- Buffer Composition: TSM III (10 mM Tris, 100 nM NaCl, 1 mM MgCl2, 0.1% Gelatin, 0.3% Microcide III, pH 7.0)
- Storage at -15 to -30°C
Features & Benefits
Reduced Complexity
- Available as standalone catalog item
- High-quality solution to monitor extraction and process efficiency
- Compatible with a wide range of RNA-based clinical assays
- Non-infectious, synthetic constructs simplify shipping and storage
Optimized Workflow
- Deployable as extractable, exogenous internal positive control
- Tailored sequences specific to SARS-CoV-2 and RNase P
- Degradation resistant in majority of biological matrices
- Multiple volume and manufacturing options available
- Available as cGMP or development lot in a range of fill volumes
Quality Performance
- Concentration determined using National Institute of Standards (NIST) traceable standard
- Highly standardized, quality controlled manufacturing ensures reliability and consistency between lots
- Manufactured in a cell-free system
Armoring Process Flow
SARS-CoV-2
Targets the N1, N2 region of the CDC recommended Diagnostic Panel (CDC-006-00019).
SARS-CoV-2 Panel
SARS-CoV-2 SV2
Ordering Information
Detailed Sequences
SARS-CoV-2 and RNase P View Detailed Sequences
SARS-CoV2 Panel View Detailed Sequences
SARS-CoV2 SV2 View Detailed Sequences
* For Research Use Only. Not For Use in Diagnostic Procedures.
Armored RNA Quant® SARS-CoV-2 Controls
Asuragen has developed molecular diagnostic controls for multiple regions of the SARS-CoV-2 genome including mutations in the spike protein prevalent in the Alpha (B.1.1.7), Beta (B.1.351), Gamma (B.1.1.28), Delta (B.1.617.2), and Omicron (B.1.1.529) strains. Armored RNA Quant® controls allow for stable, reliable and safe ways to rapidly test for the presence of SARS-CoV-2 and its variants.
Each control encodes in vitro transcribed RNA encapsulated in a protective protein coat to create a virus-like particle resistant to nuclease degradation. This allows the product to be used as RNA extraction controls, process quality controls, or positive diagnostic reference controls. From feasibility to clinical use, these robust and versatile controls are beneficial across all sectors of the research and diagnostic spectrum.
Armored RNA Quant® SARS-CoV-2 Controls
- Concentration: 1 x 106 copies/mL and can be customized
- Buffer Composition: TSM III (10 mM Tris, 100 nM NaCl, 1 mM MgCl2, 0.1% Gelatin, 0.3% Microcide III, pH 7.0)
- Storage at -15 to -30°C