AmplideX® Nanopore Carrier Plus Kit*†
A Long-Range PCR and Long-Read Sequencing Solution for Carrier Screening Research
The AmplideX® Nanopore Carrier Plus Kit has one workflow for nine high-prevalence carrier screening conditions across 11 genes providing additional insights through long-read sequencing. Most of the conditions are hard-to-decipher by short-read sequencing. The design utilizes four mixes across the 11 genes with modularity to allow any combination of testing.
Figure 1A. Panel design of 11 genes across 4 tubes Figure 1B. Different genetic variations detected and analyzed by the assay
One Workflow, Nine High-Prevalence Carrier Screening Conditions, 11 Genes
- Consolidated Workflow – Single, flexible workflow designed to consolidate existing assays and methods.
- Greater Insight – The use of long-read sequencing provides additional insight compared to existing methods (e.g. AGG interruptions in FMR1), reducing the need for reflex testing.
- Integrated Data Analysis – The AmplideX Reporter software further simplifies data analysis and reporting for a seamless, streamlined workflow.
Figure 2. High level assay workflow for the AmplideX Nanopore Carrier Plus Kit
About Our Partnership
Asuragen will leverage its gold-standard PCR technology with Oxford Nanopore’s long-read DNA sequencing capabilities to develop the first sequencing system to identify the most challenging yet high prevalence carrier genes in a single, unified workstream that today requires multiple other methods.
Learn More About Our Partnership
Product Features
Additional Resources
Videos
Scientific Posters
- Accurate Genotyping of Complex, Clinically-Relevant Variants in 11 Hard-to-Decipher Genes by Combining Novel PCR Chemistries with Any-length Nanopore Sequencing
- A PCR/Nanopore Assay for Accurate Variant Detection in Hard-to-Decipher Carrier Screening Genes with Automated Analysis Software
- An Amplification-based, Nanopore Carrier Screening Panel Resolves ClinicallyRelevant Variants in CFTR, SMN1/2, HBA1/2, HBB, and FMR1 in a Unified Workflow
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Disclaimer
*For Research Use Only. Not for use in diagnostic procedures.
†This product is under development; performance characteristics and final product features to be determined.
Trademarks and registered trademarks are the property of their respective owners.
AmplideX® Nanopore Carrier Plus Kit*†
A Long-Range PCR and Long-Read Sequencing Solution for Carrier Screening Research
The AmplideX® Nanopore Carrier Plus Kit has one workflow for nine high-prevalence carrier screening conditions across 11 genes providing additional insights through long-read sequencing. Most of the conditions are hard-to-decipher by short-read sequencing. The design utilizes four mixes across the 11 genes with modularity to allow any combination of testing.
Figure 1A. Panel design of 11 genes across 4 tubes Figure 1B. Different genetic variations detected and analyzed by the assay
One Workflow, Nine High-Prevalence Carrier Screening Conditions, 11 Genes
- Consolidated Workflow – Single, flexible workflow designed to consolidate existing assays and methods.
- Greater Insight – The use of long-read sequencing provides additional insight compared to existing methods (e.g. AGG interruptions in FMR1), reducing the need for reflex testing.
- Integrated Data Analysis – The AmplideX Reporter software further simplifies data analysis and reporting for a seamless, streamlined workflow.
Figure 2. High level assay workflow for the AmplideX Nanopore Carrier Plus Kit
About Our Partnership
Asuragen will leverage its gold-standard PCR technology with Oxford Nanopore’s long-read DNA sequencing capabilities to develop the first sequencing system to identify the most challenging yet high prevalence carrier genes in a single, unified workstream that today requires multiple other methods.
Learn More About Our Partnership
Product Features
Additional Resources
Videos
Scientific Posters
- Accurate Genotyping of Complex, Clinically-Relevant Variants in 11 Hard-to-Decipher Genes by Combining Novel PCR Chemistries with Any-length Nanopore Sequencing for Carrier Screening
- A PCR/Nanopore Assay for Accurate Variant Detection in Hard-to-Decipher Carrier Screening Genes with Automated Analysis Software
- Amplification-Based Nanopore Sequencing Accurately Detects HBA and HBB SNVs, Indels, and Structural Variants in Clinical Thalassemia Samples
- An Amplification-based, Nanopore Carrier Screening Panel Resolves ClinicallyRelevant Variants in CFTR, SMN1/2, HBA1/2, HBB, and FMR1 in a Unified Workflow
Disclaimer
*For Research Use Only. Not for use in diagnostic procedures.
†This product is under development; performance characteristics and final product features to be determined.
Trademarks and registered trademarks are the property of their respective owners.